Biological warfare, also known as germ warfare, is the use of biological toxins or infectious agents such as bacteria, viruses, insects, and fungi with the intent to kill, harm, or incapacitate humans, animals, or plants as an act of war. Biological weapons (often termed "bio-weapons", "biological threat agents", or "bio-agents") are living organisms or replicating entities ( i.e. viruses, which are not universally considered "alive"). It is probably germ warfare right now.
Biological warfare is
distinct from warfare involving other types of weapons
of mass destruction (WMD),
including nuclear
warfare, chemical warfare, and radiological
warfare. None of these are
considered conventional
weapons, which are deployed
primarily for their explosive, kinetic, or incendiary potential.
Overview
As a tactical weapon for military use, a significant problem with biological warfare is that it would take days or years to be effective, and therefore might not immediately stop an opposing force. Some biological agents (smallpox, pneumonic plague) have the capability of person-to-person transmission via aerosolized respiratory droplets. This feature can be undesirable, as the agent(s) may be transmitted by this mechanism to unintended populations, including neutral or even friendly forces. During a pandemic, the government faces an incentive to not disclose negative information about vaccines to not jeopardize public vaccine acceptance, while disclosing negative information may increase hesitancy, transparency sustains trust in health authorities and hinders the spread of conspiracy beliefs, and from this situation, a vaccine can be the best candidate for a new delivery agent(s). Worse still, such a weapon could "escape" the laboratory where it was developed, even if there was no intent to use it.
Genetic warfare Bio-agents
Theoretically, novel approaches in biotechnology, such as
synthetic biology could be used in the future to design novel types of
biological warfare agents.
1.
Would demonstrate how
to render a vaccine ineffective;
2.
Would confer
resistance to therapeutically useful antibiotics or antiviral agents;
3.
Would enhance the
virulence of a pathogen or render a nonpathogen virulent;
4.
Would increase the
transmissibility of a pathogen;
5.
Would alter the host
range of a pathogen;
6. Would enable the evasion of diagnostic/detection tools; Would enable the weaponization of a biological agent or toxin.
Hypothesis Bio-agents in Experimental Covid19 vaccine
Platforms being developed in 2020 involved nucleic acid technologies (nucleoside-modified messenger RNA and DNA), non-replicating viral vectors, peptides, recombinant proteins, live attenuated viruses, and inactivated viruses.
An inactivated vaccine (or killed vaccine) is a vaccine consisting of virus particles, bacteria, or other pathogens that have been grown in culture and then killed to destroy disease-producing capacity. In contrast, live vaccines use pathogens that are still alive (but are almost always attenuated, that is, weakened). Pathogens for inactivated vaccines are grown under controlled conditions and are killed as a means to reduce infectivity and thus prevent infection from the vaccine. The virus is killed using a method such as heat or formaldehyde. Inactivated vaccines are further classified depending on the method used to inactivate the virus. Whole virus vaccines use the entire virus particle, fully destroyed using heat, chemicals, or radiation. The pathogens formulated in the experimental COVID vaccine are origin from (Bat) the first animal of concerned pathogens. Pathogen particles are destroyed and cannot divide, but the pathogens maintain some of their integrity to be recognized by the immune system and evoke an adaptive immune response. When manufactured correctly, the vaccine is not infectious, but improper inactivation can result in intact and infectious particles and can be the tools of bio-weapon agents
Hypothesis comorbid from Bio-agents
Short/Long-term Neuropathic
pain is pain caused
by damage or disease affecting the somatosensory
nervous system. Neuropathic
pain may be associated with abnormal sensations called dysesthesia or pain from normally non-painful stimuli (allodynia). It may have continuous and/or episodic (paroxysmal) components. The latter resemble stabbings or electric
shocks. Common qualities include burning or coldness, "pins and
needles" sensations, numbness, and itching.
Comorbidities
Neuropathic pain caused by virus/toxin has profound physiological effects on the brain which can manifest as
psychological disorders. Neuropathic pain has important effects on social well-being that should not be ignored. Neuropathic pain sufferers may have difficulty working exhibit higher levels of presenteeism, absenteeism, and unemployment, exhibit higher levels of substance misuse (which may be related to attempted self-medication), and present difficulties with social interactions. Moreover, uncontrolled neuropathic pain is a significant risk factor for suicide, depression, and hypertension. Certain classes of neuropathic pain may cause serious adverse effects necessitating hospital admission, for instance, trigeminal neuralgia can present as a severe crisis where the patient may have difficulty talking, eating, and drinking.Common epidemiological clues that may
signal a biological attack
From most specific to least specific:
1.
Single cause of a
certain disease caused by an uncommon agent, with lack of an epidemiological
explanation.
2.
Unusual, rare, genetically
engineered strain of an agent.
3.
High morbidity and
mortality rates in regards to patients with the same or similar symptoms.
4.
Unusual presentation
of the disease.
5.
Unusual geographic or
seasonal distribution.
6.
Stable endemic
disease, but with an unexplained increase in relevance.
7.
Rare transmission
(aerosols, food, water).
8.
No illness presented
in people who were/are not exposed to "common ventilation systems (have
separate closed ventilation systems) when illness is seen in persons in close
proximity who have a common ventilation system."
9.
Different and
unexplained diseases coexisting in the same patient without any other
explanation.
10.
Rare illness that
affects a large, disparate population (respiratory disease might suggest the
pathogen or agent was inhaled).
11.
Illness is unusual for
a certain population or age group in which it takes presence.
12.
Unusual trends of
death and/or illness in animal populations, previous to or accompanying illness
in humans.
13.
Many affected reaching
out for treatment at the same time.
14.
Similar genetic makeup
of agents in affected individuals.
15. Simultaneous collections of similar illnesses in non-contiguous areas, domestic, or foreign. An abundance of cases of unexplained diseases and deaths.
Incubation theory for
multiple mutated variants from vaccine
Escape mutation from vaccine occurs when the immune system of a host, especially of a human being, is unable to
respond to an infectious agent, or, in other words, the host's immune system is no longer able to recognize and eliminate a pathogen such as a virus. This process can occur in a number of different ways of both a genetic and environmental nature. Such mechanisms include homologous recombination and manipulation and resistance of the host's immune responses. Different antigens are able to escape through a variety of mechanisms. Antigenic escape is not only crucial for the host's natural immune response, but also for the resistance against vaccinations. The problem of antigenic escape has greatly deterred the process of creating new vaccines. Because vaccines generally cover a small ratio of strains of one virus, the recombination of antigenic DNA that leads to diverse pathogens allows these invaders to resist even newly developed vaccinations. Some antigens may even target pathways different from those the vaccine had originally intended to target.Consequences of recent vaccines
While vaccines are created to strengthen the immune response to pathogens, in many cases these vaccines are not able to cover the wide variety of strains a pathogen may have. Instead, they may only protect against one or two strains, leading to the escape of strains not covered by the vaccine. This results in the pathogens being able to attack targets of the immune system different than those intended to be targeted by the vaccination.