Infectivity of
human coronavirus plague (hCP) can begin one to three days before the onset of covid-19 symptoms. Vaccinated Infected persons can spread the plague disease even
if they are pre-symptomatic or asymptomatic. Most
commonly, the peak viral load in upper respiratory tract samples occurs close to the time of symptom onset and
declines after the first week after symptoms begin. Current evidence
suggests a duration of viral shedding and the period of infectiousness of up to
ten days following symptom onset for persons with mild to moderate COVID-19,
and up to 20 days for persons with severe COVID-19, including
immunocompromised persons. The symptom plague is not being detected indoors if the vaccinated (subject) is in good and healthy conditions.
Experimental Covid-19 Vaccine
trigger Spike Protein and created Human Coronavirus Plague (hCP)
Many vaccine technologies being developed for
COVID‑19 are not like vaccines already in use to prevent influenza, but rather are using
"next-generation" strategies for precise targeting of COVID‑19
infection mechanisms. Several synthetic vaccines use a 2P mutation
to lock the spike protein into its prefusion configuration, stimulating an adaptive immune response to the virus before it attaches to a human cell.
Timelines for conducting clinical
research – normally a sequential process requiring years – are being
compressed into safety, efficacy, and dosing trials running simultaneously over
months, potentially compromising safety assurance. The rapid development and
urgency of producing a vaccine for the COVID‑19 pandemic were expected to
increase the risks and failure rate of delivering a safe, effective vaccine.
Throughout the COVID-19
pandemic, the genome of SARS-CoV-2 viruses was sequenced many
times, resulting in the identification of thousands of distinct variants. Many
of these possess mutations that change the amino
acid sequence of
the spike protein. In a World Health Organization analysis
from July 2020, the spike (S) gene was the second most frequently
mutated in the genome, after ORF1ab (which
encodes most of the virus' nonstructural proteins).
The evolution rate in the spike gene is
higher than that observed in the genome overall. Analyses of SARS-CoV-2 genomes
suggest that some sites in the spike protein sequence, particularly in the
receptor-binding domain, are of evolutionary importance and are
undergoing positive selection.
As of September 2020, clinical development
uses adjuvants to
enhance immunogenicity. Specifically, an adjuvant may be used in formulating a COVID‑19
vaccine candidate to boost its immunogenicity and efficacy to reduce or prevent
COVID‑19 infection in vaccinated individuals, however, protection reduced
significantly in the months following vaccination.
Fully vaccinated individuals with breakthrough infections have peak viral load similar to unvaccinated cases and
can efficiently transmit coronavirus plague infection in household settings.
However, the magnitude of transmission by individuals with Delta breakthrough
infections appears to be 50% increased in unvaccinated individuals vs than in
vaccinated individuals.
Spike proteins' role in COVID-19 vaccines. were said to
be dangerously "cytotoxic"
and mRNA vaccines containing them therefore in themselves dangerous. Spike
proteins were also said to be "shed" by vaccinated people, in an
erroneous allusion to the phenomenon of vaccine-induced viral shedding, which is a rare effect of live-virus vaccines unlike those used for COVID-19. "Shedding" of
spike proteins is not possible.
Spike protein mutations raise concern because they may affect infectivity or transmissibility, or facilitate immune escape. The mutation D614G has arisen independently in multiple viral lineages and become dominant among sequenced genomes; it may have advantages in infectivity and transmissibility possibly due to increasing the density of spikes on the viral surface, increasing the proportion of binding-competent conformations, or improving stability, but it does not affect vaccines. The mutation N501Y is common to the Alpha, Beta, Gamma, and Omicron Variants of SARS-CoV-2 has contributed to enhanced infection and transmission, and reduced vaccine efficacy. The mutation P681R alters the furin cleavage site and has been responsible for increased infectivity, transmission, and global impact of the SARS-CoV-2 Delta variant. Mutations at position E484, particularly E484K, have been associated with immune escape and reduced antibody binding.
The SARS-CoV-2 Omicron variant is notable for having an unusually high number of mutations in the spike protein. The SARS CoV-2 spike gene (S gene, S-gene) mutation 69–70del (Δ69-70) causes a TaqPath PCR test probe to not bind to its S gene target, leading to S gene target failure (SGTF) in SARS CoV-2 positive samples. This effect was used as a marker to monitor the propagation of the Alpha variant and the Omicron variant.Every Vaccinated Person can
be a high potential and efficient (hCP) spreader
As of 31 March 2022, 11.99 billion COVID-19 vaccine doses have been administered
worldwide, with 70 percent of the global population having received at least
one dose. While 17.03 million vaccines were then
being administered daily, only 14.4 percent of people in low-income countries
had received at least a first vaccine by March 2022, according to official
reports from national health agencies. From this data, we can estimate that around 5
billion of the global population were being inoculated fully vaccinated with
covid-19 vaccine, and the data tick up-ward daily.
The theory of human coronavirus plague (hCP) is
based on the mass global population being vaccinated and the redundancy of variant
resurfaces from covid-19 vaccine. Its symptoms are less dangerous and deadly in the early stage and can convert to very lethal and deadly when transform into
covid-19 disease.
In the early stage of human coronavirus plague
(hCP), people may feel mild headache, itching and stickiness in the skin and
throat, fatigue, muscle pain, sometimes confusion, and feel like to get a fever and cough. From this early stage,
paracetamol, honey, coconut water, orange juice, and other vitamins C-rich citrus
fruit can be used to get rid of any infection caused by this unsettled feeling.
Any mild unsettled feeling from vaccinated people can trigger spike protein
and become human coronavirus plague (hCP), to the people vaccinated or unvaccinated if one can cure it in early-stage, spike protein to trigger (hCP) can be halted. Vaccinated
people with still protected by vaccine immunity, can feel less infected compared
to the people who are unvaccinated, but vaccinated people with waning vaccine
immunity can easily infected and fall sick, from this rotation also trigger the human coronavirus plague (hCP) chain of a cluster.
We must keep our body healthy and strengthen our immune system boosters by eating more fruits and vegetables that are rich in vitamin C, E, beta carotene, and zinc to halt the spike protein of human coronavirus plague (hCP), this small effort you take, can save one life. Covid-19 is yet the deadliest disease ever, and it potentially will stay forever in our lifetimes.
Preventive measures and a Healthy lifestyle in new normal
Preventive measures to reduce the chances of infection include
getting vaccinated, staying at home, wearing a mask in public, avoiding crowded
places, keeping distance from others, ventilating indoor spaces, managing potential
exposure durations, washing hands with soap and water often and for at
least twenty seconds, practicing good respiratory hygiene, and avoiding
touching the eyes, nose, or mouth with unwashed hands.
Those diagnosed with COVID‑19 or who believe they may be
infected are advised to be quarantined and stay home except to get medical care,
call ahead before visiting a healthcare provider, wear a
face mask before entering the healthcare provider's office, and when
in any room or vehicle with another person, cover coughs and sneezes with a
tissue, regularly wash hands with soap and water and avoid sharing personal
household items.
A healthy lifestyle includes a balanced
diet. This does not mean cutting out important food groups from your
diet or limiting yourself on the number of calories per day. A well-rounded
diet involves eating most food groups in every meal. Meats, dairy, fruits, and
vegetables are all important components of a meal that will ensure your body is
healthy.
Common epidemiological warnings
The effect of repetitions covid-19 vaccine
intake is still under study and examination, but we are really sure it has a
consequences effect on the body and health of people vaccinated. The good of
science to develop pan coronavirus vaccine has
been proposed to prevent or mitigate future coronavirus epidemics and pandemics. Ahead to get an effective vaccine, we must see outcomes from the program on cases and
death statistics, at a time now, the vaccine program is the common righteous method for pandemic solutions to the people who are needed.
